KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLXIPL
All Species:
28.18
Human Site:
Y757
Identified Species:
47.69
UniProt:
Q9NP71
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP71
NP_116569.1
852
93073
Y757
M
R
D
M
F
D
D
Y
V
R
T
R
T
L
H
Chimpanzee
Pan troglodytes
XP_509441
819
90122
Y723
M
K
D
M
F
D
E
Y
V
K
T
R
T
L
Q
Rhesus Macaque
Macaca mulatta
XP_001115131
390
43669
F296
L
Q
P
S
L
D
D
F
M
D
I
S
G
S
S
Dog
Lupus familis
XP_546925
857
93734
Y762
M
R
D
M
F
D
D
Y
V
R
T
R
T
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q99MZ3
864
94857
Y769
M
R
D
M
F
D
D
Y
V
R
T
R
T
L
H
Rat
Rattus norvegicus
Q6AXT8
471
49872
G377
G
V
H
P
P
A
P
G
V
H
P
P
P
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001104311
895
97370
Y801
M
R
S
M
F
D
D
Y
V
R
S
S
T
L
H
Frog
Xenopus laevis
NP_001084764
548
60887
N454
A
S
P
T
L
T
H
N
P
S
A
T
T
F
S
Zebra Danio
Brachydanio rerio
XP_001338503
817
90800
Y721
M
R
E
K
F
D
D
Y
V
K
N
R
T
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724328
836
92381
Y736
V
R
Q
L
Y
D
I
Y
V
R
Y
N
T
M
N
Honey Bee
Apis mellifera
XP_394429
1014
115124
Y918
M
K
E
M
F
D
E
Y
V
R
T
R
T
R
E
Nematode Worm
Caenorhab. elegans
P41846
1009
112841
F910
K
T
S
L
E
T
F
F
D
R
Y
V
K
E
G
Sea Urchin
Strong. purpuratus
XP_788672
1338
148936
E1244
E
I
N
K
L
K
Q
E
I
A
G
L
H
T
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVN1
1266
139556
I1031
N
S
E
K
F
K
R
I
M
Q
T
I
L
S
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.6
42.9
87.7
N.A.
81.4
20.8
N.A.
N.A.
51.4
30.9
39.4
N.A.
20
29.5
25.5
21.1
Protein Similarity:
100
55.4
43.9
91.4
N.A.
85.7
29.3
N.A.
N.A.
60.7
41.6
53.5
N.A.
36.5
44.9
41.3
33.5
P-Site Identity:
100
73.3
13.3
100
N.A.
100
6.6
N.A.
N.A.
80
6.6
66.6
N.A.
40
66.6
6.6
0
P-Site Similarity:
100
93.3
40
100
N.A.
100
6.6
N.A.
N.A.
86.6
6.6
80
N.A.
73.3
86.6
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
0
0
8
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
29
0
0
65
43
0
8
8
0
0
0
0
8
% D
% Glu:
8
0
22
0
8
0
15
8
0
0
0
0
0
8
8
% E
% Phe:
0
0
0
0
58
0
8
15
0
0
0
0
0
8
0
% F
% Gly:
8
0
0
0
0
0
0
8
0
0
8
0
8
0
8
% G
% His:
0
0
8
0
0
0
8
0
0
8
0
0
8
0
29
% H
% Ile:
0
8
0
0
0
0
8
8
8
0
8
8
0
0
0
% I
% Lys:
8
15
0
22
0
15
0
0
0
15
0
0
8
0
0
% K
% Leu:
8
0
0
15
22
0
0
0
0
0
0
8
8
43
8
% L
% Met:
50
0
0
43
0
0
0
0
15
0
0
0
0
8
0
% M
% Asn:
8
0
8
0
0
0
0
8
0
0
8
8
0
0
8
% N
% Pro:
0
0
15
8
8
0
8
0
8
0
8
8
8
0
0
% P
% Gln:
0
8
8
0
0
0
8
0
0
8
0
0
0
0
15
% Q
% Arg:
0
43
0
0
0
0
8
0
0
50
0
43
0
8
0
% R
% Ser:
0
15
15
8
0
0
0
0
0
8
8
15
0
22
15
% S
% Thr:
0
8
0
8
0
15
0
0
0
0
43
8
65
8
0
% T
% Val:
8
8
0
0
0
0
0
0
65
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
58
0
0
15
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _